在针对性药物问世前，治疗手段十分有限且充满挑战。外科肢体延长术创伤性强、风险高，且行业内尚未形成统一诊疗共识；重组人生长激素（rhGH）虽能在一定程度上改善生长状况，但疗效有限，治疗2年后骨骼生长的有益作用便会减弱，还存在显著的长期副作用。
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At Demna’s first Gucci catwalk show, staged in Milan on Friday afternoon in front of an audience including Donatella Versace and Paris and Nicky Hilton, dresses were so short and tight that Emily Ratajkowski periodically yanked down a handful of disco-ball sequins to cover her bottom as she walked. There were lapdance-bar tinsel hair extensions, and Kate Moss in a diamante G-string. A certain sketchiness in the roll of the hips, a model who pulled his phone out of his bumbag and scrolled his way down the catwalk.